Is it possible to cut worldwide levels of interpersonal violence in half within the coming 30 years? This question was at the centre of the first Global Violence Reduction Conference 2014, jointly organised by the Violence Research Centre at the University of Cambridge and the World Health Organization. The conference lured experts out of their comfort zone, asking to reflect on big strategies to reduce violence by 50% in the next 30 years. It brought together 150 leading representatives from international organisations, academia, civil society institutions and philanthropic organisations to discuss how scientific knowledge can contribute to the advancement of this violence reduction goal. The main message of the conference was that a global violence reduction by 50% in the next 30 years is achievable if policy makers harness the power of scientific evidence on violence reduction. This report outlines important ideas presented at the conference that could help to reach this goal and groups them into six key policy recommendations.